Researchers and hospitals literally can accumulate rooms full of paperwork documenting a single clinical trial. Rick Arlow offers a better method of document management without all that paper. RegulatoryBinder is an early stage software company focused on document management for medical clinic trials.
 
Arlow, who was earning a dual M.D. and Ph.D. a year ago, observed how much paper was wasted in clinical trials, came up with the idea to go paperless. So he quit his s... Read more >

When remodeling a kitchen, people usually rely on friends for advice on contractors and architects. Brides use websites and friends as resources when planning their wedding. Entrepreneurs Brian Verne and Mike Eppich figured: Why not create a place where athletes can get advice on apparel?

So Verne and Eppich created Phenom, a mobile app where athletes can brag about the apparel and equipment they use to train. “Influences have a place,” says Verne. “Athl... Read more >

On any given night in Cleveland, it's not too difficult to see the economic impact represented by a seemingly simple glass of suds. Breweries had an undeniably positive effect on Ohio City, and now the arrival of more breweries promises to boost the economic prospects of other neighborhoods.

An east-side developer has purchased the historic streetcar power station on Larchmere Boulevard. Once home to the American Crafts Gallery, which is thought to be the oldest gallery of its kind in Cleveland and is now housed within the Dancing Sheep boutique down the road, the property has been vacant for years. Ilene Greenblatt, who has developed properties in Chicago before moving back to Cleveland to be near family, bought the building and expects to wrap up renovations by Marc... Read more >

Cleveland Neighborhood Progress, a nonprofit community development organization, has begun offering Cleveland City Life tours to expose suburbanites, millenials, empty-nesters, boomerangs and newcomers to town to all the city has to offer.

CNP Director of Marketing Jeff Kipp says the tours really are about helping Clevelanders see for themselves the positive change taking place in the city.

"We'll do the proverbial handholding and take you into the neigh... Read more >

Startups @ City Club is a new collaborative effort between the City Club of Cleveland  and the Cleveland Startup Collective to bring the startup community together in educational, social and thought-provoking environments.
 
The first event was launched at Cleveland Entrepreneurial Week in November, with speakers on technology, product development, investing and the overall startup community in Cleveland. “The main goal of the entrepreneurial speaker series... Read more >

The City of Lakewood has issued 44 certificates of occupancy on Madison Avenue this year, and nine businesses are participating in the city's storefront renovation program. Planning and Development Director Dru Siley says these numbers show how much business interest there is along this traditional yet funky strip, which is seeing a wave of redevelopment activity spurred in part by Detroit Avenue's success.

"We want to reproduce the success we've had on D... Read more >

In this, the first installment in a two-part series, Fresh Water development editor Lee Chilcote takes a close look at the Opportunity Corridor, a 3.5 mile planned roadway that would connect I-490 with University Circle. The project is being promoted as a bike- and pedestrian-friendly boulevard, but skeptics have their doubts.

Cleveland artist Jessica Newell recently quit her job teaching Psychology at Cleveland State University to open a gallery in the 5th Street Arcades. Jessica's Gallery, as it's called, functions as a studio, a gallery for the artist's work and a showcase for rotating local artists.

"I love to paint," Newell explains. "I began receiving a lot of commissions from friends and family, and pretty soon I began to realize, 'I can make a business out... Read more >

Dan Mansoor’s 30 years in nonprofit fundraising has taught him one thing. Well, it’s taught him a few things, actually. One is that people think they give to their favorite charities much more often than they actually do. Two: donor retention rates hover around only 40 percent. And three: 80 percent of charitable giving is still motivated by direct mail.
 
Mansoor thought there had to be a better way, one that makes it just as easy to make and track donati... Read more >

From bikeshares to spare couches, swapping clothing to trading tools, the sharing economy has picked up some serious steam in recent years. Thousands of micro-entrepreneurs are finding ways to capitalize on the peer-to-peer trend -- and one of them might just be the next Airbnb.

When Lisa Reed was coaching clients on health and nutrition out of her Chagrin Falls office, she would always make them a healthy green juice. After time, Reed realized that some of her customers were coming more for the juice than they were for the counseling.
 
The juice, today known as Mean Green, is made with celery, cucumber, kale, spinach, romaine and lemon. “You really feel good because your body becomes alkaline,” explains Reed. “You crave it... Read more >

This week, Brauhaus Cleveland LLC broke ground on the new Hofbrauhaus Cleveland in PlayhouseSquare in the most apropos fashion -- with a German oom-pah band, sausages and huge steins of beer. Project developers aim to complete the new restaurant and brewery by the end of 2014.

"Everything started in 1589 when the Bavarian kings decided the beer wasn't good enough for them, so they created their own brewery," extolled Maximilian Erlmeier, a former Hofbrauhaus... Read more >