A drug that has shown promise in the treatment of cardiovascular disease will now be evaluated for effectiveness in healing wounds, thanks to a joint capital investment. SironRX Therapeutics has received a $500,000 investment from Cleveland Clinic and JumpStart Ventures. The money will allow SironRX to continue evaluations on its lead drug, JVS-100, which contains an engineered version of a naturally occurring molecular factor called Stromal cell-Derived Factor-1 (SDF-1). SDF-1 pr... Read more >

Dr. Cathy Whitehouse founded The Intergeneration School (TIS), a charter school on Cleveland's east side, as a place that values children as independent learners.

"TIS takes a lifespan, developmental approach to education," she says. "We're all on a learning journey, and we should honor the uniqueness in each learner."

TIS just celebrated its 10-year anniversary. In that time, it has become one of the highest-performing schools in Cleveland, consistently earning ... Read more >

For years, the trend in Ohio City was for young couples to buy homes, live there a few years, and then flee to the suburbs when they had kids. Thanks to a close-knit group of pioneering parents, that story may soon have a different ending. With hopes for a new public charter school becoming a reality, many young parents see a future that doesn't include a home in suburbia.

Many young professionals living in the city eventually become parents, trading in their preoccupation with trendy bars for a newfound obsession with play dates, baby gates and high-quality schools.

Yet in any urban area, finding a good school can be tricky. Like the Clash song, a refrain echoes in their heads: "Should I stay or should I go?"

A new study says that for many Cleveland residents, quality public schools could make the difference between choosing to s... Read more >

Inspired by one of Mahatma Ghandi's famous mantras -- "we must become the change we wish to see in the world" -- Open Yoga Gallery, a yoga studio with a mission, will launch this weekend at 4736 Lorain Avenue in Ohio City.

"One of our goals is to get people onto the yoga mat for the first time," says April Arotin, the studio's founder. To that end, Open Yoga offers several classes per week that merely suggest a donation. During the opening weekend, the studio will offer ... Read more >

According to BioEnterprise, Cleveland continues to be a leader in the Midwest when it comes to raising money for start-up healthcare companies. Last year, healthcare-related start-ups in Cleveland raised just over $135 million in investments. Cleveland was third in the Midwest in start-up allocations behind Chicago and Minneapolis, according to the Midwest Healthcare Venture Report released by Cleveland's BioEnterprise, which supports the growth of bioscience enterprises.

... Read more >

Steve Arless has nearly four decades of experience in the medical-device industry. As president and CEO of CryoCath, he grew the company to more than 300 employees before arranging its sale for $380 million. Now, he brings his expertise to Cleveland in hopes of doing the same for CardioInsight, which is developing a cardiac arrhythmia ablation therapy.

Some said it would never happen, but the day is finally arriving: A groundbreaking ceremony for the Cleveland Medical Mart and Convention Center takes place this Friday, January 14. Construction has already gotten underway near Lakeside Avenue, though, signifying that the much-anticipated, often-controversial $465 million project will become a reality. Completion of the project is expected to be sometime in 2013.

For many, the building's external progress will be almost a... Read more >

Making good on a 2010 goal to build and strengthen its interests in the healthcare industry, The Riverside Company this month announced the acquisition of Physicians Pharmacy Alliance (PPA). The North Carolina-based company specializes in drug dispensing to at-home chronically ill patients. PPA was founded in 2002 and has been recognized as one of the fastest growing companies in the region by the Triangle Business Journal.

Riverside, a private equity firm with offic... Read more >

The recent announcement of a $1.1 million grant from the U.S. Department of Agriculture to create urban farms along Kinsman Avenue is just one example of the growing power of the green movement in Cleveland's urban neighborhoods.

Another example is the 2009 award of a $75,000 grant from the U.S. EPA to help create Neighborhood Leadership for Environmental Health (NLEH), a partnership between three nonprofits to improve the environmental health of four east side neighborh... Read more >

When it comes to rainfall, we tend to focus on keeping it off of our heads -- not where it goes after hitting the pavement. Yet storm water runoff is a major issue in Northeast Ohio. With every downpour, millions of gallons of rainwater run off parking lots, streets and sidewalks, carrying pollutants into our streams, rivers and Lake Erie.

A new program launched by the Northeast Ohio Regional Sewer District (NEORSD) in December aims to address Combined Sewer Overflows (C... Read more >

In a laboratory at Case Western Reserve University's School of Medicine, Zhenghe John Wang and a team of researchers developed a panel of new human isogenic cell models, which look much like mutated cancer cells. Through these cell models, researchers can get a handle on how cancer takes shape in the human body.

"We actually created a technology where we can add tags into cancer cells so we can track them," says Wang, assistant professor of genetics at Case's School of Me... Read more >

That small-fish-in-a-big-pond feeling is likely to crop up now and again for local doctors who choose to work outside of one of the large hospital systems. One of the big problem areas? Managing automated tasks like medical records and insurance reimbursements. Any independent physician in Northeast Ohio who has ever felt alone in this realm will want to check out the newly launched Independent Physician Solutions (IPS) from Sisters of Charity Health System.

IPS offers in... Read more >