Health + Wellness
cleveland goes from butt of hollywood jokes to a hub of innovation
In a lengthy feature titled "Hiding Out in Ohio: Bioscience," Tom Thriveni, writing for the digital mag Ozymandias, covers the burgeoning bioscience industry in Cleveland.
"Just as robotics companies in Pittsburgh and high-speed fiber-optic networks in Chattanooga have helped transform the economies of those cities, bioscience entrepreneurship has reshaped Cleveland’s sagging economy," he writes.
"The [Cleveland Heartlab and Cleveland Clinic] partnership was initiated by the clinic as part of its mission to turn its inventions into commercially viable medical products, generating profits for both parties. To date, besides Heartlab, 66 neighboring companies have spun out from Cleveland Clinic ideas since 2000. All told, the clinic has 525 patents and 450 licensing agreements."
Read the rest of the good news here.
"Just as robotics companies in Pittsburgh and high-speed fiber-optic networks in Chattanooga have helped transform the economies of those cities, bioscience entrepreneurship has reshaped Cleveland’s sagging economy," he writes.
"The [Cleveland Heartlab and Cleveland Clinic] partnership was initiated by the clinic as part of its mission to turn its inventions into commercially viable medical products, generating profits for both parties. To date, besides Heartlab, 66 neighboring companies have spun out from Cleveland Clinic ideas since 2000. All told, the clinic has 525 patents and 450 licensing agreements."
Read the rest of the good news here.
The City of Cleveland has installed 40 recycling bins downtown as part of its "ongoing efforts to increase recycling bins and materials diverted from landfills," according to a press release from the Office of Sustainability. The bins, which are being funded by Cleveland’s Energy Efficiency and Conservation Block Grant (EECBG) Program, are being rolled out as part of the Year of Zero Waste, which is part of Mayor Jackson's Sustainable Cleveland initiative.
“The presence of recycling bins downtown is a visible way for residents, employees and tourists to understand that Cleveland is committed to sustainability and to do their part by recycling,” said Jenita McGowan, Chief of Sustainability, in a release. “These bins not only provide opportunities for the public to recycle in high traffic areas downtown, but also increase the City’s recycling rates. We look forward to collecting metric information from these bins to inform future expansion of recycling in public spaces.”
The blue-lidded recycle bins have been placed next to existing waste receptacles. They are located between West 9th Street and East 12th Street from Lakeside Avenue to Prospect Avenue, and there are also some locations on Euclid Avenue near Playhouse Square and Cleveland State University.
For more information on the Year of Zero Waste, click here.
Source: Jenita McGowan
Writer: Lee Chilcote
“The presence of recycling bins downtown is a visible way for residents, employees and tourists to understand that Cleveland is committed to sustainability and to do their part by recycling,” said Jenita McGowan, Chief of Sustainability, in a release. “These bins not only provide opportunities for the public to recycle in high traffic areas downtown, but also increase the City’s recycling rates. We look forward to collecting metric information from these bins to inform future expansion of recycling in public spaces.”
The blue-lidded recycle bins have been placed next to existing waste receptacles. They are located between West 9th Street and East 12th Street from Lakeside Avenue to Prospect Avenue, and there are also some locations on Euclid Avenue near Playhouse Square and Cleveland State University.
For more information on the Year of Zero Waste, click here.
Source: Jenita McGowan
Writer: Lee Chilcote
Cleveland continues to gain momentum in leading the country and the Midwest in biomedical investments, according to BioEnterprise’s 2013 Midwest Healthcare Venture Investment Report. The report, released last month, shows that while overall investing is down nationwide, biomedical investments in health IT and medical devices in Northeast Ohio continue to be on the rise.
Ohio ranked number-one in healthcare venture investments. Cleveland earned the number-two regional ranking with $201.2 million invested in 50 companies, second only to Minneapolis. “It’s a very strong report, particularly for medical devices in the Midwest,” says Aram Nerpouni, president and CEO of BioEnterprise. “There is a strong pipeline of companies coming out of the Cleveland area.”
This is the second year the Cleveland area has seen $200 million in venture capital coming into the medical field, according to Nerpouni. But the ranking has taken years of effort. “As a region, it’s something we’ve been working toward for a decade now,” he says, crediting the area’s healthcare systems, universities and savvy entrepreneurs with the investment increase.
Ten years ago Cleveland’s leaders recognized the region’s assets in the biomedical field and have worked to create a reputation. But Nerpouni cautions we are only just beginning. “Look at it as a very good start,” he says. “We have to strike a balance of celebrating the progress but not getting too confident that it’s automatic.”
Nerpouni cites institutions like Cleveland Clinic Innovations, the Global Cardiovascular Innovation Center, and University Hospitals’ Harrington Discovery Institute, and now the Global Center for Health Innovation as just some of the contributors to the region’s growth in the biomedical field.
“Look at how much growth has happened, we’re just seeing this steady progress,” he says. “You begin to find there’s this flywheel gaining momentum.”
Source: Aram Nerpouni
Writer: Karin Connelly
Ohio ranked number-one in healthcare venture investments. Cleveland earned the number-two regional ranking with $201.2 million invested in 50 companies, second only to Minneapolis. “It’s a very strong report, particularly for medical devices in the Midwest,” says Aram Nerpouni, president and CEO of BioEnterprise. “There is a strong pipeline of companies coming out of the Cleveland area.”
This is the second year the Cleveland area has seen $200 million in venture capital coming into the medical field, according to Nerpouni. But the ranking has taken years of effort. “As a region, it’s something we’ve been working toward for a decade now,” he says, crediting the area’s healthcare systems, universities and savvy entrepreneurs with the investment increase.
Ten years ago Cleveland’s leaders recognized the region’s assets in the biomedical field and have worked to create a reputation. But Nerpouni cautions we are only just beginning. “Look at it as a very good start,” he says. “We have to strike a balance of celebrating the progress but not getting too confident that it’s automatic.”
Nerpouni cites institutions like Cleveland Clinic Innovations, the Global Cardiovascular Innovation Center, and University Hospitals’ Harrington Discovery Institute, and now the Global Center for Health Innovation as just some of the contributors to the region’s growth in the biomedical field.
“Look at how much growth has happened, we’re just seeing this steady progress,” he says. “You begin to find there’s this flywheel gaining momentum.”
Source: Aram Nerpouni
Writer: Karin Connelly
In college, Glenn Harbold followed family tradition and pursued a degree in mechanical and aerospace engineering. While he was interested in the manufacturing process, Harbold quickly realized that he possessed an entrepreneurial spirit and wanted to be a part of bringing new products to market.
That curiosity and spirit led Harbold to buy into Zounds Hearing as a franchisee. He is opening his first of six stores in the area on February 10th, in Brooklyn.
“My career has been a bit of a winding road, but I’m really into entrepreneurship,” Harbold says. After a stint in engineering, Harbold went on to earn an MBA and moved to Cleveland to work with two local technology startups. “I enjoyed getting up every day knowing that the future was in the hands of a small group of people.”
Then last year, Harbold began looking for companies to acquire. He met Sam Thomasson, a fellow engineer and founder of Zounds Hearing. “Sam is an electrical engineer and I loved his passion,” says Harbold. “We really hit it off.”
Harbold was so impressed with the quality and affordability of Zounds hearing aids that he decided to buy into the company. “The price and quality of the technology are really special,” he says. “We’re going to make it a lot easier for some people who couldn’t previously afford high quality hearing aids.”
After the Brooklyn store, Harbold plans to open five more stores in the area. He will employ two people at the Brooklyn store, including an audiologist and a client care specialist. Long-term, he predicts he will employ 12 to 15 people in the six stores.
Source: Glenn Harbold
Writer: Karin Connelly
That curiosity and spirit led Harbold to buy into Zounds Hearing as a franchisee. He is opening his first of six stores in the area on February 10th, in Brooklyn.
“My career has been a bit of a winding road, but I’m really into entrepreneurship,” Harbold says. After a stint in engineering, Harbold went on to earn an MBA and moved to Cleveland to work with two local technology startups. “I enjoyed getting up every day knowing that the future was in the hands of a small group of people.”
Then last year, Harbold began looking for companies to acquire. He met Sam Thomasson, a fellow engineer and founder of Zounds Hearing. “Sam is an electrical engineer and I loved his passion,” says Harbold. “We really hit it off.”
Harbold was so impressed with the quality and affordability of Zounds hearing aids that he decided to buy into the company. “The price and quality of the technology are really special,” he says. “We’re going to make it a lot easier for some people who couldn’t previously afford high quality hearing aids.”
After the Brooklyn store, Harbold plans to open five more stores in the area. He will employ two people at the Brooklyn store, including an audiologist and a client care specialist. Long-term, he predicts he will employ 12 to 15 people in the six stores.
Source: Glenn Harbold
Writer: Karin Connelly
Long winters (and the occasional polar vortex) are just something we have to live with around here. However, those bold enough to venture into Cleveland's great white waste will find a flurry of cold weather activities that extend beyond the usual realm of skiing, inner-tubing and tobogganing.
On the heels of a successful merger that brought together under one roof three nonprofit community development organizations, Cleveland Neighborhood Progress (CNP) has made a key hire to lead its policy and advocacy efforts. Alesha Washington, a Glenville native who most recently served as Director of Executive Administration and Government Relations at the Centers for Family and Children, recently joined CNP as its Senior Director of Advocacy, Policy and Research. Washington will lead strategic policy initiatives at the city, county, state and federal levels and identify and use academic research to inform community development strategies.
"Trying to create a shared advocacy platform for the CDC community is what attracted me to the role," says Washington. "There's a need and a longing for a very coordinated and aligned system. The goal is to work together to improve Cleveland's neighborhoods for all people."
"It's about connecting the dots," adds Joel Ratner, President of CNP. "The needs we're identifying at the neighborhood level should be articulated clearly, strongly and strategically to officials who are setting policy and government budgets."
In recent years, Ratner says, no such coordinated effort has existed. Policy priorities might include strategies and funding to address vacant and abandoned properties, maintaining and enhancing tax credit programs that lend to neighborhood development, and influencing the state budget.
Source: Alesha Washington, Joel Ratner
Writer: Lee Chilcote
"Trying to create a shared advocacy platform for the CDC community is what attracted me to the role," says Washington. "There's a need and a longing for a very coordinated and aligned system. The goal is to work together to improve Cleveland's neighborhoods for all people."
"It's about connecting the dots," adds Joel Ratner, President of CNP. "The needs we're identifying at the neighborhood level should be articulated clearly, strongly and strategically to officials who are setting policy and government budgets."
In recent years, Ratner says, no such coordinated effort has existed. Policy priorities might include strategies and funding to address vacant and abandoned properties, maintaining and enhancing tax credit programs that lend to neighborhood development, and influencing the state budget.
Source: Alesha Washington, Joel Ratner
Writer: Lee Chilcote
Cleveland Neighborhood Progress has awarded $340,000 to nine community development corporations for green space improvements in Cleveland neighborhoods. The funds, which stem from the WellsFargo CityLIFT program as part of a multimillion dollar national settlement, will be used to fund side yards, pocket parks, pathway parks and street-edge improvements across the city.
"We feel this is very impactful," says Joel Ratner, President of Cleveland Neighborhood Progress. "Every day there are more vacant lots in Cleveland. The vast majority of them are scattered sites. How do we repurpose them in a way that supports neighborhoods? Urban agriculture is great, but you usually need larger pieces of land. This is a way of supporting the people that live on these streets."
Through a competitive process, CNP awarded funds to a pocket park adjacent to the E. 79th Street rapid station in Central, a pathway park in Tremont, and side yards in Stockyards, Brooklyn Centre and Clark-Fulton, among others.
The work will be completed on these lots in the spring and summer of 2014, with all improvements slated to be completed by November 2014.
"This is about the psychology of the neighborhood on some basic level," says Ratner. "It shows people their neighborhoods have not been forgotten. There may be many development opportunities in the medium or long-term future, but in the meantime, we want to keep the streets as strong as possible."
The grants were awarded as part of ReImagining Cleveland 3.0, a program whose earlier rounds fostered urban agriculture and greening projects across Cleveland.
Cleveland has been recognized nationally as a leader in urban agriculture and neighborhood greening as a response to population loss and the foreclosure crisis.
Source: Joel Ratner
Writer: Lee Chilcote
"We feel this is very impactful," says Joel Ratner, President of Cleveland Neighborhood Progress. "Every day there are more vacant lots in Cleveland. The vast majority of them are scattered sites. How do we repurpose them in a way that supports neighborhoods? Urban agriculture is great, but you usually need larger pieces of land. This is a way of supporting the people that live on these streets."
Through a competitive process, CNP awarded funds to a pocket park adjacent to the E. 79th Street rapid station in Central, a pathway park in Tremont, and side yards in Stockyards, Brooklyn Centre and Clark-Fulton, among others.
The work will be completed on these lots in the spring and summer of 2014, with all improvements slated to be completed by November 2014.
"This is about the psychology of the neighborhood on some basic level," says Ratner. "It shows people their neighborhoods have not been forgotten. There may be many development opportunities in the medium or long-term future, but in the meantime, we want to keep the streets as strong as possible."
The grants were awarded as part of ReImagining Cleveland 3.0, a program whose earlier rounds fostered urban agriculture and greening projects across Cleveland.
Cleveland has been recognized nationally as a leader in urban agriculture and neighborhood greening as a response to population loss and the foreclosure crisis.
Source: Joel Ratner
Writer: Lee Chilcote
As an investor in Biolectrics, a company that makes a battery-powered mouthpiece – think sports mouth guard -- that treats periodontal diseases with electric stimulation, Paul Ruflin began thinking about the device’s potential in other applications.
“The mouthpiece delivers a small amount of current that kills oral bacteria,” Ruflin explains. “In the lab it kills 75 to 100 percent of bacteria in the mouth in five to 10 minutes. The early results are promising in killing oral bacteria.”
With human trials completed at the University of Buffalo, Ruflin has created Animal Oralectrics, based out of MAGNET’s offices. The company uses the same technology as Biolectrics but applies it toward dogs, sheep, cows and cats. “Animals are five percent more likely to have periodontal disease than humans,” says Ruflin. “Less than one percent of dog owners brush their dogs’ teeth or takes them to the vet for a cleaning.”
Ruflin recently created a prototype on a 3D printer and is working with Ohio State University College of Veterinary Medicine to test Animal Oralectrics on dogs. So far, the response has been positive. “This device kills oral bacteria, prevents gingivitis and gum loss,” explains Ruflin. “The current is undetectable. The concept here is to make a device that gives treatment but looks like a chew toy or pull toy. You can even put a treat in the end of it. The key is getting them to engage with it for five to 15 minutes.”
The Innovation Fund recently awarded Animal Oralectrics a $25,000 grant to further develop its product. Currently, the company consists of just Ruflin and an intern from CWRU. But he plans to hire a marketing and social media person soon. He also plans on running a crowd funding campaign before releasing the product in of 2014.
Ultimately, Ruflin predicts he will add seven to 10 direct employees and another 15 to 20 indirect employees over the next two or three years.
Source: Paul Ruflin
Writer: Karin Connelly
“The mouthpiece delivers a small amount of current that kills oral bacteria,” Ruflin explains. “In the lab it kills 75 to 100 percent of bacteria in the mouth in five to 10 minutes. The early results are promising in killing oral bacteria.”
With human trials completed at the University of Buffalo, Ruflin has created Animal Oralectrics, based out of MAGNET’s offices. The company uses the same technology as Biolectrics but applies it toward dogs, sheep, cows and cats. “Animals are five percent more likely to have periodontal disease than humans,” says Ruflin. “Less than one percent of dog owners brush their dogs’ teeth or takes them to the vet for a cleaning.”
Ruflin recently created a prototype on a 3D printer and is working with Ohio State University College of Veterinary Medicine to test Animal Oralectrics on dogs. So far, the response has been positive. “This device kills oral bacteria, prevents gingivitis and gum loss,” explains Ruflin. “The current is undetectable. The concept here is to make a device that gives treatment but looks like a chew toy or pull toy. You can even put a treat in the end of it. The key is getting them to engage with it for five to 15 minutes.”
The Innovation Fund recently awarded Animal Oralectrics a $25,000 grant to further develop its product. Currently, the company consists of just Ruflin and an intern from CWRU. But he plans to hire a marketing and social media person soon. He also plans on running a crowd funding campaign before releasing the product in of 2014.
Ultimately, Ruflin predicts he will add seven to 10 direct employees and another 15 to 20 indirect employees over the next two or three years.
Source: Paul Ruflin
Writer: Karin Connelly
In this, the second installment in a two-part series, Fresh Water development editor Lee Chilcote takes a close look at the Opportunity Corridor, a 3.5 mile planned roadway that would connect I-490 with University Circle. The project is being promoted as an economic development engine, but skeptics have their doubts.
Cleveland Neighborhood Progress, a nonprofit community development organization, has begun offering Cleveland City Life tours to expose suburbanites, millenials, empty-nesters, boomerangs and newcomers to town to all the city has to offer.
CNP Director of Marketing Jeff Kipp says the tours really are about helping Clevelanders see for themselves the positive change taking place in the city.
"We'll do the proverbial handholding and take you into the neighborhoods," he says. "You see the positive headlines and positive trends, but a big chunk of our population doesn't have firsthand experience with the city. This is about removing that intimidation factor and bridging the gap."
Tours starts in Ohio City and include stops in Detroit Shoreway, the lakefront, University Circle, Little Italy, Midtown, downtown and Tremont. Along the way, it also touches on neighborhoods such as Cudell, Glenville and Fairfax. Each lasts two hours, costs $12 and comes with a free Live!Cleveland/City Life T-shirt.
"As we drive through University Circle, we can reference the excitement that's happening in North Shore Collinwood," Kipp explains, adding that while the tours can't feasibly cover the whole city, they will highlight all city neighborhoods.
The tours are being marketed through CNP's website and partner organizations such as Global Cleveland and the Downtown Cleveland Alliance. There currently are tours scheduled between Christmas and New Year's and around the Martin Luther King, Jr. holiday weekend.
"This is a way to roll out the red carpet and give a reintroduction to your Cleveland neighbors," Kipp adds.
Source: Jeff Kipp
Writer: Lee Chilcote
CNP Director of Marketing Jeff Kipp says the tours really are about helping Clevelanders see for themselves the positive change taking place in the city.
"We'll do the proverbial handholding and take you into the neighborhoods," he says. "You see the positive headlines and positive trends, but a big chunk of our population doesn't have firsthand experience with the city. This is about removing that intimidation factor and bridging the gap."
Tours starts in Ohio City and include stops in Detroit Shoreway, the lakefront, University Circle, Little Italy, Midtown, downtown and Tremont. Along the way, it also touches on neighborhoods such as Cudell, Glenville and Fairfax. Each lasts two hours, costs $12 and comes with a free Live!Cleveland/City Life T-shirt.
"As we drive through University Circle, we can reference the excitement that's happening in North Shore Collinwood," Kipp explains, adding that while the tours can't feasibly cover the whole city, they will highlight all city neighborhoods.
The tours are being marketed through CNP's website and partner organizations such as Global Cleveland and the Downtown Cleveland Alliance. There currently are tours scheduled between Christmas and New Year's and around the Martin Luther King, Jr. holiday weekend.
"This is a way to roll out the red carpet and give a reintroduction to your Cleveland neighbors," Kipp adds.
Source: Jeff Kipp
Writer: Lee Chilcote
The City of Lakewood has issued 44 certificates of occupancy on Madison Avenue this year, and nine businesses are participating in the city's storefront renovation program. Planning and Development Director Dru Siley says these numbers show how much business interest there is along this traditional yet funky strip, which is seeing a wave of redevelopment activity spurred in part by Detroit Avenue's success.
"We want to reproduce the success we've had on Detroit, recognizing that Madison has unique character and flavor that make it distinct," he says. "Madison is a small business corridor. Of 300 businesses here, 95 percent of them are locally owned."
Siley says that Madison is home to independent restaurants and entertainment spots, professional services and service-oriented retail. Current vacancy rates hover around 14 percent, down from over 20 percent a few years ago. Lakewood is developing a new streetscape along Madison that will break ground fall of 2014. The city also is committing storefront renovation dollars to help attract businesses and redevelop properties.
Examples of new businesses attracted to Madison recently include Mahall's, a historic old-school bowling alley that has new ownership and added music, food and entertainment, and Barrio, a Mexican eatery. The streetscape project not only will resurface the street, but also reduce Madison to two lanes with a center turning lane to make it safer and accommodate bike lanes. No parking will be lost.
The City of Lakewood and LakewoodAlive hosted a forum entitled "Madison on the Move" on Wednesday, December 4th at Harrison Elementary School in Lakewood.
Source: Dru Siley
Writer: Lee Chilcote
"We want to reproduce the success we've had on Detroit, recognizing that Madison has unique character and flavor that make it distinct," he says. "Madison is a small business corridor. Of 300 businesses here, 95 percent of them are locally owned."
Siley says that Madison is home to independent restaurants and entertainment spots, professional services and service-oriented retail. Current vacancy rates hover around 14 percent, down from over 20 percent a few years ago. Lakewood is developing a new streetscape along Madison that will break ground fall of 2014. The city also is committing storefront renovation dollars to help attract businesses and redevelop properties.
Examples of new businesses attracted to Madison recently include Mahall's, a historic old-school bowling alley that has new ownership and added music, food and entertainment, and Barrio, a Mexican eatery. The streetscape project not only will resurface the street, but also reduce Madison to two lanes with a center turning lane to make it safer and accommodate bike lanes. No parking will be lost.
The City of Lakewood and LakewoodAlive hosted a forum entitled "Madison on the Move" on Wednesday, December 4th at Harrison Elementary School in Lakewood.
Source: Dru Siley
Writer: Lee Chilcote
Eric Klein, chair of the Glickman Urology and Kidney Institute at the Cleveland Clinic, along with a team of researchers at the Clinic and Genomic Health, have developed a genomic test that determines the aggressiveness of prostate cancer and therefore helps doctors and patients decide the proper course of treatment.
“It’s a biopsy-based test that looks at how certain genes are turned on or off,” explains Klein. “Before it was developed we made an educated guess on how aggressive a man’s tumor was based on factors like age and health.”
Often there are multiple small tumors in prostate cancer. The Oncoptype DX Prostate Cancer test, developed for market by California-based Genomic Health, looks at the activity of certain genes within the tumor. Based on the results, treatment can range from surveillance to more aggressive treatment.
“We developed it in a way to tell what else is going on in the prostate,” says Klein. “About 20 to 25 percent of men who have this test are re-assigned to a different category of progression.”
Klein is pleased with what the test means for the treatment of prostate cancer. “First, it identifies those who have more aggressive cancer,” he says. “Second, it reassures those who choose surveillance.”
Klein has spent the past eight years developing the prostate genomic test. The University of California San Francisco spent three years validating the method, and it was released in May. The test is one of many advancements in genome-guided solid tumor analysis recognized by Cleveland Clinic Innovations as the number-two innovation in health care this year. Genomic Health has a similar test for treatment of breast cancer.
“This is the first foray into precision treatment for prostate cancer,” Klein says. “With this test a management decision can be made based on the characteristics of the tumor. It’s individual decision making based on that person’s disease. That’s’ where we want to be.”
Source: Eric Klein
Writer: Karin Connelly
“It’s a biopsy-based test that looks at how certain genes are turned on or off,” explains Klein. “Before it was developed we made an educated guess on how aggressive a man’s tumor was based on factors like age and health.”
Often there are multiple small tumors in prostate cancer. The Oncoptype DX Prostate Cancer test, developed for market by California-based Genomic Health, looks at the activity of certain genes within the tumor. Based on the results, treatment can range from surveillance to more aggressive treatment.
“We developed it in a way to tell what else is going on in the prostate,” says Klein. “About 20 to 25 percent of men who have this test are re-assigned to a different category of progression.”
Klein is pleased with what the test means for the treatment of prostate cancer. “First, it identifies those who have more aggressive cancer,” he says. “Second, it reassures those who choose surveillance.”
Klein has spent the past eight years developing the prostate genomic test. The University of California San Francisco spent three years validating the method, and it was released in May. The test is one of many advancements in genome-guided solid tumor analysis recognized by Cleveland Clinic Innovations as the number-two innovation in health care this year. Genomic Health has a similar test for treatment of breast cancer.
“This is the first foray into precision treatment for prostate cancer,” Klein says. “With this test a management decision can be made based on the characteristics of the tumor. It’s individual decision making based on that person’s disease. That’s’ where we want to be.”
Source: Eric Klein
Writer: Karin Connelly