Health + Wellness
new grant program funds business incubator, other innovative community projects
A new grant program launched by Neighborhood Progress Inc., a nonprofit organization that provides funding and technical assistance to community development corporations in Cleveland, recently awarded $200,000 to five projects. The recipients include a new business incubation program in North Collinwood, youth programming in Ohio City and surrounding neighborhoods, an effort in Central to teach fourth graders about healthy, local food, arts-based development in St. Clair Superior, and a community engagement effort in Tremont.
"The program came to be when we, as an organization, made a decision to develop a program that all CDCs had access to," says Colleen Gilson, Vice President of CDC Services for NPI, of the Neighborhood Solutions grant program. "The idea was, let's not be prescriptive. Let's let CDCs tell us what their solution to a neighborhood problem is or a cool project in their service area."
The awards break down as follows: NPI awarded $45,000 to ActiVacant, a program to recruit entrepreneurs to vacant retail spaces on E. 185th; $45,000 to Near West Recreation to expand its network of youth programming, including baseball, soccer, softball, basketball and bowling; $45,000 to St. Clair Superior for its Urban Upcycle project; $45,000 to Burton Bell Carr for its Urban Farm Diet Program; and $20,000 to Tremont West for its efforts to engage residents in creating a community-based development plan around MetroHealth.
Gilson says the projects reflect "deep collaboration" and non-traditional approaches towards community development. For instance, Near West Recreation is an effort to engage and retain families in six neighborhoods on the near west side -- Ohio City, Tremont, Stockyards, Clark-Fulton and Detroit Shoreway -- and build "intergenerational mixed-income neighborhoods." ActiVacant, spearheaded by Northeast Shores, is a "new take on the American dream" and a "business incubation project on steroids" that will entice young retailers to fill empty spaces on E. 185th by offering them free or reduced rent for a period of time, access to mentors and other support, and incentives for meeting benchmarks.
"The process was pretty amazing," says Gilson, describing a Shark Tank-esque format in which finalists presented in front of a panel of community development leaders, who then ranked and voted on winners. "We invited other CDCs to come watch and learn from their peers, and it was a really good opportunity to learn."
Source: Colleen Gilson
Writer: Lee Chilcote
"The program came to be when we, as an organization, made a decision to develop a program that all CDCs had access to," says Colleen Gilson, Vice President of CDC Services for NPI, of the Neighborhood Solutions grant program. "The idea was, let's not be prescriptive. Let's let CDCs tell us what their solution to a neighborhood problem is or a cool project in their service area."
The awards break down as follows: NPI awarded $45,000 to ActiVacant, a program to recruit entrepreneurs to vacant retail spaces on E. 185th; $45,000 to Near West Recreation to expand its network of youth programming, including baseball, soccer, softball, basketball and bowling; $45,000 to St. Clair Superior for its Urban Upcycle project; $45,000 to Burton Bell Carr for its Urban Farm Diet Program; and $20,000 to Tremont West for its efforts to engage residents in creating a community-based development plan around MetroHealth.
Gilson says the projects reflect "deep collaboration" and non-traditional approaches towards community development. For instance, Near West Recreation is an effort to engage and retain families in six neighborhoods on the near west side -- Ohio City, Tremont, Stockyards, Clark-Fulton and Detroit Shoreway -- and build "intergenerational mixed-income neighborhoods." ActiVacant, spearheaded by Northeast Shores, is a "new take on the American dream" and a "business incubation project on steroids" that will entice young retailers to fill empty spaces on E. 185th by offering them free or reduced rent for a period of time, access to mentors and other support, and incentives for meeting benchmarks.
"The process was pretty amazing," says Gilson, describing a Shark Tank-esque format in which finalists presented in front of a panel of community development leaders, who then ranked and voted on winners. "We invited other CDCs to come watch and learn from their peers, and it was a really good opportunity to learn."
Source: Colleen Gilson
Writer: Lee Chilcote
Shaker Heights entrepreneur Kai Wingo recently launched the Buckeye Mushroom Farm on a vacant lot on E. 127th Street off Buckeye Road. Wingo is growing oyster and garden giant mushrooms on beds and racks there. She also teaches classes and sells mushrooms under the moniker Kai's Kultured Mushrooms at the Coit Road Farmers Market.
"I'm a mushroom ambassador," she says. "I want people to know about benefits we get from mushrooms. I'm the only one I know of who's doing it at this scale."
Wingo began growing mushrooms four years ago, and launched her business when she got laid off from her job with the Cleveland Municipal School District. By then, she'd outgrown her home garden, so she applied for a vacant lot through the land bank. Recently, she also built a hoop house there to extend the growing season.
"Mushrooms are a powerhouse of nutrition," she explains. "The gardens also benefit because of the compost they provide. They're just a grand recycler."
Wingo says there is great untapped demand for local mushrooms, which are a high-value crop, and that her business and classes are taking off. "There's a long waiting list of farmers markets that would love to have mushrooms there, but there aren't any people to fill the niche, so that's why I'm teaching people."
Hough entrepreneur Mansfield Frazier also has tapped Wingo to grow 'shrooms at his new biocellar project. She can be reached via Facebook or by phone at 216-561-3200.
Source: Kai Wingo
Writer: Lee Chilcote
"I'm a mushroom ambassador," she says. "I want people to know about benefits we get from mushrooms. I'm the only one I know of who's doing it at this scale."
Wingo began growing mushrooms four years ago, and launched her business when she got laid off from her job with the Cleveland Municipal School District. By then, she'd outgrown her home garden, so she applied for a vacant lot through the land bank. Recently, she also built a hoop house there to extend the growing season.
"Mushrooms are a powerhouse of nutrition," she explains. "The gardens also benefit because of the compost they provide. They're just a grand recycler."
Wingo says there is great untapped demand for local mushrooms, which are a high-value crop, and that her business and classes are taking off. "There's a long waiting list of farmers markets that would love to have mushrooms there, but there aren't any people to fill the niche, so that's why I'm teaching people."
Hough entrepreneur Mansfield Frazier also has tapped Wingo to grow 'shrooms at his new biocellar project. She can be reached via Facebook or by phone at 216-561-3200.
Source: Kai Wingo
Writer: Lee Chilcote
Among Tremont residents, it's a running joke that the area has almost as many dogs and cats as people. Now this pet-friendly neighborhood will gain another asset in the form of the Tremont Animal Clinic, which is set to open on W. 14th Street by the end of the year.
"We grew up in Cleveland, born and bred," says Katie McCoy, who is opening the clinic with fellow veterinarians Sara Tippins and Bob Litkovitz (known as "Dr. Bob" to all who frequent Gateway Animal Clinic, where he and Litkovitz has worked for years). "We looked at Independence, Hinckley, but always came back to wanting to be a part of the city. We walk down the street and see people we know. Tremont is a nice, small, supportive community, and we love that."
Tremont Animal Clinic will be a full-service clinic that offers appointment times and segregated examination rooms. The vets decided to open the clinic to offer an alternative to Gateway, which is walk-in only and has large, open rooms. The facility will be open Monday through Saturday, and will be open until 7:30 p.m. at least one evening per week.
The building, located at 3148 W. 14th Street, is the former home of the Rodeo Bar, a nuisance that Tremont residents have complained about for years. Local entrepreneur and Treehouse owner Tom Leneghan is completely renovating the place, having gutted it down to the studs. A hair and nail salon is located next door, and a barbeque joint called Nana's BBQ is slated to go in on the other side.
"People were so happy to see us go in here because the Rodeo had been a problem for years," says McCoy, who is aiming for a soft opening before Christmas.
Source: Katie McCoy
Writer: Lee Chilcote
"We grew up in Cleveland, born and bred," says Katie McCoy, who is opening the clinic with fellow veterinarians Sara Tippins and Bob Litkovitz (known as "Dr. Bob" to all who frequent Gateway Animal Clinic, where he and Litkovitz has worked for years). "We looked at Independence, Hinckley, but always came back to wanting to be a part of the city. We walk down the street and see people we know. Tremont is a nice, small, supportive community, and we love that."
Tremont Animal Clinic will be a full-service clinic that offers appointment times and segregated examination rooms. The vets decided to open the clinic to offer an alternative to Gateway, which is walk-in only and has large, open rooms. The facility will be open Monday through Saturday, and will be open until 7:30 p.m. at least one evening per week.
The building, located at 3148 W. 14th Street, is the former home of the Rodeo Bar, a nuisance that Tremont residents have complained about for years. Local entrepreneur and Treehouse owner Tom Leneghan is completely renovating the place, having gutted it down to the studs. A hair and nail salon is located next door, and a barbeque joint called Nana's BBQ is slated to go in on the other side.
"People were so happy to see us go in here because the Rodeo had been a problem for years," says McCoy, who is aiming for a soft opening before Christmas.
Source: Katie McCoy
Writer: Lee Chilcote
Abeona Therapeutics, a small biotech startup company that develops therapies for lysomal storage diseases, earned the Global Gene’s Champion of Hope award, along with its partners, for its work in developing therapies for children with Sanfilippo Syndrome, a rare genetic disorder.
Abeona, founded earlier this year in Cleveland as a spinoff of Columbus-based Nationwide Children’s Hospital, is developing two products that came out of research at Nationwide. ABX-A and ABX-B have the potential to cure Sanfilippo Syndrome.
Children with Sanfilippo are missing an essential enzyme for normal cellular function, causing toxins in their brains and bodies to cause severe disabilities. Symptoms often appear in the first year of life, causing progressive muscular and cognitive decline, and the disease is usually fatal by the early teens.
Current studies show that a single dose of Abeona’s treatments prompted cells to produce the missing enzymes and help repair the damage.
“What’s unique about this drug is that it’s a collaboration between Abeona, the hospital and eight international foundations to find a treatment for Sanfilippo Syndrome,” says Abeona president and CEO Tim Miller.
Abeona’s products are a result of 10 years of research done by Nationwide’s Haiyan Fu. Abeona is currently raising money to conduct phase I and II clinical trials in 2014. “One of the things that drew me to this company is the pre-clinical data for these drugs,” says Miller. “The life span is improved. If this transfers over to the kids I’ll be very excited.”
While there are no approved treatments for Sanfilippo Syndrome yet, Miller says a number of companies are working on therapies.
Source: Tim Miller
Writer: Karin Connelly
Abeona, founded earlier this year in Cleveland as a spinoff of Columbus-based Nationwide Children’s Hospital, is developing two products that came out of research at Nationwide. ABX-A and ABX-B have the potential to cure Sanfilippo Syndrome.
Children with Sanfilippo are missing an essential enzyme for normal cellular function, causing toxins in their brains and bodies to cause severe disabilities. Symptoms often appear in the first year of life, causing progressive muscular and cognitive decline, and the disease is usually fatal by the early teens.
Current studies show that a single dose of Abeona’s treatments prompted cells to produce the missing enzymes and help repair the damage.
“What’s unique about this drug is that it’s a collaboration between Abeona, the hospital and eight international foundations to find a treatment for Sanfilippo Syndrome,” says Abeona president and CEO Tim Miller.
Abeona’s products are a result of 10 years of research done by Nationwide’s Haiyan Fu. Abeona is currently raising money to conduct phase I and II clinical trials in 2014. “One of the things that drew me to this company is the pre-clinical data for these drugs,” says Miller. “The life span is improved. If this transfers over to the kids I’ll be very excited.”
While there are no approved treatments for Sanfilippo Syndrome yet, Miller says a number of companies are working on therapies.
Source: Tim Miller
Writer: Karin Connelly
The Cleveland Clinic marks its 50th year of successful kidney transplants this year. While the Clinic was not the first to successfully transplant a human kidney, the hospital was, and continues to be, a pioneer in the field.
“There were two earlier transplants,” explains Robert Heyka, interim chair of the department of nephrology and hypertension at the Clinic’s Glickman Urological and Kidney Institute. “One was in New Jersey, but it only lasted 10 months. The first successful transplant was in 1954, in Boston, which worked because the transplant occurred with identical twins.”
The Cleveland Clinic performed its first successful kidney transplant in 1963, in part due to the development of anti-rejection drugs, and in part because Willem Kolff, a doctor from the Netherlands, came to the Clinic in the 1950s with his dialysis machine.
Kolff’s original dialysis machines were made with a washing machine motor, a nose cone borrowed from NASA and peach cans. He perfected his machine at the Clinic. Dialysis made it possible to keep patients alive while they waited for a transplant. “A combination of medications and the Cleveland Clinic having dialysis machines made the program successful,” says Heyka.
In 1966, the Cleveland Clinic performed 126 kidney transplants. Additionally, Cleveland was one of the first cities to establish an independent organ procurement program in the late 1960s. The organization now is known as Lifebanc.
Today, the Clinic has transplanted more than 4,200 kidneys and is on track to perform 200 transplants this year. The Glickman Urological and Kidney Institute ranked second this year in U.S. News and World Report’s America’s Best Hospitals.
“All these things we take for granted now as standard and mass produced,” says Heyka. “When you get into it, it’s more inspiring when you hear about the people who did it first and the challenges they had to face.”
Writer: Karin Connelly
Source: Robert Heyka
“There were two earlier transplants,” explains Robert Heyka, interim chair of the department of nephrology and hypertension at the Clinic’s Glickman Urological and Kidney Institute. “One was in New Jersey, but it only lasted 10 months. The first successful transplant was in 1954, in Boston, which worked because the transplant occurred with identical twins.”
The Cleveland Clinic performed its first successful kidney transplant in 1963, in part due to the development of anti-rejection drugs, and in part because Willem Kolff, a doctor from the Netherlands, came to the Clinic in the 1950s with his dialysis machine.
Kolff’s original dialysis machines were made with a washing machine motor, a nose cone borrowed from NASA and peach cans. He perfected his machine at the Clinic. Dialysis made it possible to keep patients alive while they waited for a transplant. “A combination of medications and the Cleveland Clinic having dialysis machines made the program successful,” says Heyka.
In 1966, the Cleveland Clinic performed 126 kidney transplants. Additionally, Cleveland was one of the first cities to establish an independent organ procurement program in the late 1960s. The organization now is known as Lifebanc.
Today, the Clinic has transplanted more than 4,200 kidneys and is on track to perform 200 transplants this year. The Glickman Urological and Kidney Institute ranked second this year in U.S. News and World Report’s America’s Best Hospitals.
“All these things we take for granted now as standard and mass produced,” says Heyka. “When you get into it, it’s more inspiring when you hear about the people who did it first and the challenges they had to face.”
Writer: Karin Connelly
Source: Robert Heyka
The Enterprise Nurture an Idea Crowdrise Challenge offers entrepreneurs the opportunity to win $10,000 by competing to raise the most money online. Eleven innovative ideas in Cleveland are competing between now and November 8th for that big grand prize.
Ideas include a bike composting business in Gordon Square, an initiative to open retail startups in former shipping containers in downtown parking lots, a healthy corner store in Tremont, and a food cooperative distribution center in St. Clair Superior.
Daniel Brown of Rust Belt Gardens studied successful operations in other cities before setting his sights on launching a bike composting business. He says that such a business not only can be profitable, but also can help homeowners divert waste from landfills, create green-collar jobs and improve soil at community gardens.
"We need to buy specialized bikes and trailers, get the website up and running, and start to educate people about what is compostable and not compostable," Brown says of his startup. His partners in the challenge are Detroit Shoreway Community Development, Bike Cleveland and Groundz Recycling.
Cleveland Bike Composting would charge $10 to $25 per month to pick up five-gallon compost buckets from a home or business, depending on how often it is scheduled.
"At our community garden, we can't compost enough," says Brown of the demand. "Purchasing compost is expensive, but the process to make it is fairly easy if you know what you're doing. People in Cleveland are really buying into the local foods movement, and that lends itself to there being demand for a composting service."
Currently, there is no business in Cleveland that helps individual homeowners to compost, much less that does so by bike, which raises the sustainability to a new level of green.
Source: Daniel Brown
Writer: Lee Chilcote
Ideas include a bike composting business in Gordon Square, an initiative to open retail startups in former shipping containers in downtown parking lots, a healthy corner store in Tremont, and a food cooperative distribution center in St. Clair Superior.
Daniel Brown of Rust Belt Gardens studied successful operations in other cities before setting his sights on launching a bike composting business. He says that such a business not only can be profitable, but also can help homeowners divert waste from landfills, create green-collar jobs and improve soil at community gardens.
"We need to buy specialized bikes and trailers, get the website up and running, and start to educate people about what is compostable and not compostable," Brown says of his startup. His partners in the challenge are Detroit Shoreway Community Development, Bike Cleveland and Groundz Recycling.
Cleveland Bike Composting would charge $10 to $25 per month to pick up five-gallon compost buckets from a home or business, depending on how often it is scheduled.
"At our community garden, we can't compost enough," says Brown of the demand. "Purchasing compost is expensive, but the process to make it is fairly easy if you know what you're doing. People in Cleveland are really buying into the local foods movement, and that lends itself to there being demand for a composting service."
Currently, there is no business in Cleveland that helps individual homeowners to compost, much less that does so by bike, which raises the sustainability to a new level of green.
Source: Daniel Brown
Writer: Lee Chilcote
A grassroots urban placemaking movement that started in Portland has made its way to Cleveland, and a few weeks ago, residents from three Cleveland neighborhoods came together to remove blight with community-led art.
City Repair, which started in Portland as a guerilla movement to add splashes of color to city streets, is so new here that the City of Cleveland denied a permit request at the last minute, forcing organizers to scramble to adapt their project. The original idea was to paint city intersections, and Cleveland officials now acknowledge that they need a new policy to deal with these requests.
In the end, City Repair Cleveland created three successful projects and built a greater sense of community in the process, says Adele DiMarco-Kious, consultant to the effort.
"This is about neighbors getting to know one another and taking shared action about things important to them in their neighborhood," she adds. "You get people to come together, take ownership of the public realm and start taking action and it has a multiplier effect. People build trust, take action and build a sense of power."
In Buckeye-Shaker Square, residents created a vision for a mural that they hope will be painted on a bridge over the RTA tracks that historically has divided their two neighborhoods; Clark-Fulton residents beautified the long-neglected Newark Court alley by painting a mural of the river that once ran through the community; and Stockyard residents covered up a blighted retaining wall with colorful designs.
DiMarco-Kious says the impact goes far beyond the physical projects themselves, as neighbors work shoulder-to-shoulder and families come out of their houses to help paint.
City Repair Cleveland was supported by Neighborhood Connections, a small grants and community building program affiliated with the Cleveland Foundation.
Source: Adele DiMarco-Kious
Writer: Lee Chilcote
City Repair, which started in Portland as a guerilla movement to add splashes of color to city streets, is so new here that the City of Cleveland denied a permit request at the last minute, forcing organizers to scramble to adapt their project. The original idea was to paint city intersections, and Cleveland officials now acknowledge that they need a new policy to deal with these requests.
In the end, City Repair Cleveland created three successful projects and built a greater sense of community in the process, says Adele DiMarco-Kious, consultant to the effort.
"This is about neighbors getting to know one another and taking shared action about things important to them in their neighborhood," she adds. "You get people to come together, take ownership of the public realm and start taking action and it has a multiplier effect. People build trust, take action and build a sense of power."
In Buckeye-Shaker Square, residents created a vision for a mural that they hope will be painted on a bridge over the RTA tracks that historically has divided their two neighborhoods; Clark-Fulton residents beautified the long-neglected Newark Court alley by painting a mural of the river that once ran through the community; and Stockyard residents covered up a blighted retaining wall with colorful designs.
DiMarco-Kious says the impact goes far beyond the physical projects themselves, as neighbors work shoulder-to-shoulder and families come out of their houses to help paint.
City Repair Cleveland was supported by Neighborhood Connections, a small grants and community building program affiliated with the Cleveland Foundation.
Source: Adele DiMarco-Kious
Writer: Lee Chilcote
Researcher J. Mark Brown and his team at the Cleveland Clinic Lerner Research Institute have discovered a protein that might promote obesity and diabetes. Therefore, blocking that protein, called ABHD6, might prevent these diseases.
ABHD6 regulates the brain’s endocannabinoid system, which is involved in metabolism, cravings and hunger.
Brown discovered ABHD6’s role in fat storage while studying a mutation in a different protein in the same group, ABHD5. “Normally, fat is stored in triglyceride tissue,” Brown explains. “With abnormal ABHD5, fat is stored in every other cell in the body. In studying that we discovered a crucial breakdown in ABHD6 and we decided to study it.”
Brown conducted a study in mice to see how fat was stored in ABHD6, to see if it impacted type-2 diabetes, obesity and fatty liver disease. He found that blocking the protein’s function had a direct impact on these diseases.
The research indicates that blocking function of ABHD6 in mice protects against all diseases driven by eating a high-fat diet. Further research could actually lead to a pill that would block ABHD6, and therefore prevent obesity.
Brown’s findings were published last week in the journal Cell Reports. “Our paper will be the first that shows the importance of the enzyme in regulating the way the body stores fat,” explains Brown, who has spent the past four years researching ABHD6.
“It’s hard to say if it would ever end up being a magic pill to cure obesity,” says Brown. “We look at it like a preventative measure. We’re really excited to move forward with it and conduct safety trials with humans. We know it works in mice, so it’s very important to translate our findings into human studies as quickly as we can.”
Source: J. Mark Brown
Writer: Karin Connelly
ABHD6 regulates the brain’s endocannabinoid system, which is involved in metabolism, cravings and hunger.
Brown discovered ABHD6’s role in fat storage while studying a mutation in a different protein in the same group, ABHD5. “Normally, fat is stored in triglyceride tissue,” Brown explains. “With abnormal ABHD5, fat is stored in every other cell in the body. In studying that we discovered a crucial breakdown in ABHD6 and we decided to study it.”
Brown conducted a study in mice to see how fat was stored in ABHD6, to see if it impacted type-2 diabetes, obesity and fatty liver disease. He found that blocking the protein’s function had a direct impact on these diseases.
The research indicates that blocking function of ABHD6 in mice protects against all diseases driven by eating a high-fat diet. Further research could actually lead to a pill that would block ABHD6, and therefore prevent obesity.
Brown’s findings were published last week in the journal Cell Reports. “Our paper will be the first that shows the importance of the enzyme in regulating the way the body stores fat,” explains Brown, who has spent the past four years researching ABHD6.
“It’s hard to say if it would ever end up being a magic pill to cure obesity,” says Brown. “We look at it like a preventative measure. We’re really excited to move forward with it and conduct safety trials with humans. We know it works in mice, so it’s very important to translate our findings into human studies as quickly as we can.”
Source: J. Mark Brown
Writer: Karin Connelly
The City of Euclid recently completed Phase I of its ambitious Waterfront Improvements Plan, creating an expanded fishing pier, a new multi-purpose trail and an accessible switchback ramp to the lakefront.
Euclid Mayor Bill Cervenik says the $1.7 million project is part of a larger, $30 million push to expand Euclid's waterfront with a new, three-quarter mile beachfront and marina that he hopes will become a regional draw.
"We want to re-establish the historic beaches along the shoreline and make sure they're accessible, as Cleveland and the Metroparks are trying to do," he says.
Phase I of the waterfront plan was funded by $1.4 million from the City of Euclid and $355,000 from the State of Ohio. The city will seek additional aid to support future phases of the plan. "We'll be stopped dead in our tracks if we don't have assistance from the federal, state and county governments," Cervenik says.
Euclid now owns the majority of the three-quarter mile stretch of lakefront thanks to a donation from the K&D Group, a large apartment developer that owns lakefront property.
Over the long-term, Cervenik envisions a paved multi-purpose path along the entire stretch of cobble beach, which would include restored natural habitat. He also envisions sailing and kayak lessons and boating at the new marina once built.
For now, Euclid residents and visitors can enjoy the revitalized Sims Park, which Cervenik says complements nearly $14 million of recent development downtown.
Source: Bill Cervenik
Writer: Lee Chilcote
Euclid Mayor Bill Cervenik says the $1.7 million project is part of a larger, $30 million push to expand Euclid's waterfront with a new, three-quarter mile beachfront and marina that he hopes will become a regional draw.
"We want to re-establish the historic beaches along the shoreline and make sure they're accessible, as Cleveland and the Metroparks are trying to do," he says.
Phase I of the waterfront plan was funded by $1.4 million from the City of Euclid and $355,000 from the State of Ohio. The city will seek additional aid to support future phases of the plan. "We'll be stopped dead in our tracks if we don't have assistance from the federal, state and county governments," Cervenik says.
Euclid now owns the majority of the three-quarter mile stretch of lakefront thanks to a donation from the K&D Group, a large apartment developer that owns lakefront property.
Over the long-term, Cervenik envisions a paved multi-purpose path along the entire stretch of cobble beach, which would include restored natural habitat. He also envisions sailing and kayak lessons and boating at the new marina once built.
For now, Euclid residents and visitors can enjoy the revitalized Sims Park, which Cervenik says complements nearly $14 million of recent development downtown.
Source: Bill Cervenik
Writer: Lee Chilcote
NovelMed Therapeutics, a biotech company founded in 2003 that develops treatments for macular degeneration, announced that it has developed an antibody compound that is effective in treating wet age-related macular degeneration (AMD) and possibly the dry form of the disease as well. AMD affects more than two million people in the United States and is a leading cause of blindness among adults.
Two independent pre-clinical investigations showed that NovelMed's lead compound, an alternative pathway inhibitor, prevents wet-AMD. “We believe our technology inhibits the progression of AMD,” says Rekha Bansal, CEO and founder of NovelMed. “The animal data supports treatment for wet AMD. The compound could possibly treat the dry form as well, which accounts for 90 percent of the AMD market.”
Bansal says the therapy currently is in the manufacturing phase, with safety studies scheduled to begin next year and human clinical trials to start in late 2014.
“I think we are at the forefront in time with the potential to treat both wet and dry AMD,” says Bansal. “It’s the first treatment of its kind.”
Bansal is proud that this breakthrough is happening in Northeast Ohio. “This is a drug coming out of Cleveland for vision loss,” she says. “It’s going to be a great thing for Cleveland.”
NovelMed currently has four R&D positions open due to its recent growth.
Source: Rekha Bansal
Writer: Karin Connelly
Two independent pre-clinical investigations showed that NovelMed's lead compound, an alternative pathway inhibitor, prevents wet-AMD. “We believe our technology inhibits the progression of AMD,” says Rekha Bansal, CEO and founder of NovelMed. “The animal data supports treatment for wet AMD. The compound could possibly treat the dry form as well, which accounts for 90 percent of the AMD market.”
Bansal says the therapy currently is in the manufacturing phase, with safety studies scheduled to begin next year and human clinical trials to start in late 2014.
“I think we are at the forefront in time with the potential to treat both wet and dry AMD,” says Bansal. “It’s the first treatment of its kind.”
Bansal is proud that this breakthrough is happening in Northeast Ohio. “This is a drug coming out of Cleveland for vision loss,” she says. “It’s going to be a great thing for Cleveland.”
NovelMed currently has four R&D positions open due to its recent growth.
Source: Rekha Bansal
Writer: Karin Connelly
Modern medicine is constantly innovating ways to improve the length and quality of human life. Cleveland researchers are leading the way with cutting-edge treatments and technologies that can blast a brain tumor with a laser, detect a concussion using an iPad, and test for prostate cancer by way of genetics.
Cleveland's economic leaders have worked hard to parade the city as a hub for innovation. A chance to further show off Northeast Ohio's entrepreneurial acumen is a driving force behind Shaker Heights accelerator LaunchHouse's sponsorship of Cleveland Entrepreneurship Week (Cleveland EW), an upcoming four-day celebration of business success.
The event, scheduled for November 4-8, was created to give entrepreneurs and investors the knowledge and resources to grow the Northeast Ohio business community, says LaunchHouse co-founder Todd Goldstein.
LaunchHouse will kick off Cleveland EW at its Shaker Heights headquarters by presenting the 11 technology startups participating in its Accelerator Program. The rest of the week will feature speakers and other events that give entrepreneurs from all over the country an opportunity to connect with potential financial backers as well as fellow businesspeople.
"We're giving them exposure to people they normally wouldn't meet," says Goldstein. "Meeting the right person can help turn a small business into a large business."
LaunchHouse pushing for the entrepreneurship event aligns with its mission of local job creation through seed capital, education and innovation, notes Goldstein. With Cleveland striving to be on the forefront of the new economy, an event like Cleveland EW can put the area in a positive national spotlight.
"We've worked to change how Northeast Ohio is viewed in terms of entrepreneurship," Goldstein says. "This [event] is about showcasing the region as a place of innovation and capital formation."
SOURCE: Todd Goldstein
WRITER: Douglas J. Guth
The event, scheduled for November 4-8, was created to give entrepreneurs and investors the knowledge and resources to grow the Northeast Ohio business community, says LaunchHouse co-founder Todd Goldstein.
LaunchHouse will kick off Cleveland EW at its Shaker Heights headquarters by presenting the 11 technology startups participating in its Accelerator Program. The rest of the week will feature speakers and other events that give entrepreneurs from all over the country an opportunity to connect with potential financial backers as well as fellow businesspeople.
"We're giving them exposure to people they normally wouldn't meet," says Goldstein. "Meeting the right person can help turn a small business into a large business."
LaunchHouse pushing for the entrepreneurship event aligns with its mission of local job creation through seed capital, education and innovation, notes Goldstein. With Cleveland striving to be on the forefront of the new economy, an event like Cleveland EW can put the area in a positive national spotlight.
"We've worked to change how Northeast Ohio is viewed in terms of entrepreneurship," Goldstein says. "This [event] is about showcasing the region as a place of innovation and capital formation."
SOURCE: Todd Goldstein
WRITER: Douglas J. Guth
Ninety two percent of residents in the Central neighborhood live below 200 percent of the poverty line, qualifying them to receive food from food pantries. Yet until recently, the future of the city's largest food pantry -- and the second-largest food pantry in Cuyahoga County -- was seriously in doubt.
Recently, the Society of St. Vincent de Paul of Cleveland (SVDP) stepped in to assume management of Brother Hubbard's Cupboard in the Carl Stokes Building at 6001 Woodland Avenue, which serves 1,700 people per month and over 20,000 annually.
"The need is still going up based on the number of people we're serving at food pantries, and the working poor tend to be the last ones affected by an economic upswing in a positive way," says John Litten, Executive Director of SVDP. "Northeast Ohio has been slower to recover than we've been led to believe."
The pantry previously was managed by the Capuchin Franciscan Brothers under the direction of Brother Walt Robb, but was in danger of closing when it was announced that Robb was leaving for another assignment.
Litten says SVDP has risen to the task of managing a massive food pantry that requires almost daily deliveries from the Cleveland Food Bank. Yet he stresses that it's about a lot more than just giving out food. "It's the human side that really gets to our mission, the person-to-person service," he says. "For many people, this may be the only person who's helping you today, smiling at you, asking how you're doing."
Although word is still getting out about the newly renamed SVDP Woodland Pantry, Litten says it's already making a difference. "The impact on the neighborhood is huge."
Source: John Litten
Writer: Lee Chilcote
Recently, the Society of St. Vincent de Paul of Cleveland (SVDP) stepped in to assume management of Brother Hubbard's Cupboard in the Carl Stokes Building at 6001 Woodland Avenue, which serves 1,700 people per month and over 20,000 annually.
"The need is still going up based on the number of people we're serving at food pantries, and the working poor tend to be the last ones affected by an economic upswing in a positive way," says John Litten, Executive Director of SVDP. "Northeast Ohio has been slower to recover than we've been led to believe."
The pantry previously was managed by the Capuchin Franciscan Brothers under the direction of Brother Walt Robb, but was in danger of closing when it was announced that Robb was leaving for another assignment.
Litten says SVDP has risen to the task of managing a massive food pantry that requires almost daily deliveries from the Cleveland Food Bank. Yet he stresses that it's about a lot more than just giving out food. "It's the human side that really gets to our mission, the person-to-person service," he says. "For many people, this may be the only person who's helping you today, smiling at you, asking how you're doing."
Although word is still getting out about the newly renamed SVDP Woodland Pantry, Litten says it's already making a difference. "The impact on the neighborhood is huge."
Source: John Litten
Writer: Lee Chilcote
ny times gives ink to new rust belt mag 'belt'
In a New York Times Arts Beat post titled “New Magazine Celebrates ‘Rust Belt Chic,’ With a Wink,” writer Jennifer Schuessler details her conversation with Belt magazine editor Anne Trubek about a new publication dedicated to fostering a new journalistic beat in Cleveland.
"The decaying cities of the post-industrial Midwest can sometimes seem like a museum of things America used to make: cars, refrigerators, steel, televisions. But if a start-up in Cleveland gets its way, the region may help rebuild the market for another endangered product -- long-form magazine journalism," Schuessler writes.
The magazine offers up a collection of essays and reporting that seeks to explore the regional identity that is known as the Rust Belt.
“I cringe at words like ‘authentic,’” Trubek says in the article. “But the rust belt aesthetic isn’t about the ephemeral global economy, it’s about boots on the ground and things hidden in grandma’s attic. We want to explore that.”
Check out the full interview here.
"The decaying cities of the post-industrial Midwest can sometimes seem like a museum of things America used to make: cars, refrigerators, steel, televisions. But if a start-up in Cleveland gets its way, the region may help rebuild the market for another endangered product -- long-form magazine journalism," Schuessler writes.
The magazine offers up a collection of essays and reporting that seeks to explore the regional identity that is known as the Rust Belt.
“I cringe at words like ‘authentic,’” Trubek says in the article. “But the rust belt aesthetic isn’t about the ephemeral global economy, it’s about boots on the ground and things hidden in grandma’s attic. We want to explore that.”
Check out the full interview here.
Core and shell renovations of the 150,000-square-foot Victory Center, a $26 million project located along the Health-Tech Corridor, are almost complete. Tenant build-outs will follow, and although none have signed leases yet, developer Scott Garson says that will change as his team finishes the common spaces and shows the property to more prospective tenants.
"Everybody thinks it's wonderful, great… The trick is getting the first one in," he says. "I have enough letters of intent out there that I'm confident it's only a matter of time."
Garson says the demand is there for flexible, ready-to-grow office space geared towards biomedical, research and technology companies, which is why he decided to undertake the project. He points out that nearby buildings owned by Geis Companies and Cumberland Development are almost completely full.
So far, Garson has completed the project without a bank loan, using partner equity and a $720,000 loan from the city, $2.5 million in tax increment financing, federal and state historic tax credits, and a $1 million State of Ohio job ready sites grant. Garson expects to secure bank financing in the near future for tenant build-outs.
The building's unique features include a new interior with a historic waffle slab ceiling, window wells that allow plenty of natural light, copious backup power, fiber-optic connectivity, and the right mechanicals in place for laboratory space. The building will be certified LEED Silver, saving tenants 20 percent on utility costs. Finally, it has views of downtown, free parking and HealthLine access.
"We went through a recycling program with the materials and our landscaping uses stormwater management strategies," says Michael Augoustidis of Domukur Architects, the firm that designed the project. "It's very energy-efficient."
Although he's not ready to declare victory yet, Gardon says the historic building, which was built in 1917 as the Arts Center, is nearing the goal line and ready to score.
Source: Scott Garson
Writer: Lee Chilcote
"Everybody thinks it's wonderful, great… The trick is getting the first one in," he says. "I have enough letters of intent out there that I'm confident it's only a matter of time."
Garson says the demand is there for flexible, ready-to-grow office space geared towards biomedical, research and technology companies, which is why he decided to undertake the project. He points out that nearby buildings owned by Geis Companies and Cumberland Development are almost completely full.
So far, Garson has completed the project without a bank loan, using partner equity and a $720,000 loan from the city, $2.5 million in tax increment financing, federal and state historic tax credits, and a $1 million State of Ohio job ready sites grant. Garson expects to secure bank financing in the near future for tenant build-outs.
The building's unique features include a new interior with a historic waffle slab ceiling, window wells that allow plenty of natural light, copious backup power, fiber-optic connectivity, and the right mechanicals in place for laboratory space. The building will be certified LEED Silver, saving tenants 20 percent on utility costs. Finally, it has views of downtown, free parking and HealthLine access.
"We went through a recycling program with the materials and our landscaping uses stormwater management strategies," says Michael Augoustidis of Domukur Architects, the firm that designed the project. "It's very energy-efficient."
Although he's not ready to declare victory yet, Gardon says the historic building, which was built in 1917 as the Arts Center, is nearing the goal line and ready to score.
Source: Scott Garson
Writer: Lee Chilcote
Cleveland Clinic Innovations has launched a spinoff company, Shield Biotech, out of the Lerner Research Institute. Led by Vincent Tuohy, the company is developing a vaccine for breast cancer.
The vaccine uses the body’s own immune system to fight off and kill cancerous tumors. Tuohy, who serves as Shield’s chief science officer, has been working on this theory for the past 11 years.
The next step is to secure FDA approval for human clinical trials, probably within the next two years. Researchers found that a single vaccination could prevent breast tumors from occurring in mice genetically bred to develop breast cancer, while also inhibiting the growth of already existing breast tumors. The research was originally published in Nature Medicine in 2010.
“It works in animals,” says Tuohy. “It’s safe and very effective. We’d like to see women live longer without tumors, not women live longer with tumors.”
Tuohy sees the vaccine as particularly effective in breast cancers that are aggressive and tend to recur. “Triple-negative breast cancer has a higher recurrence rate than other forms of breast cancer and is insensitive to current forms of adjuvant therapy,” he says. “It’s the predominant form of breast cancer that occurs, for example, in women with BRCA1 mutations. “
Tuohy sees potential in eventually immunizing against prostrate and ovarian cancers as well.
Source: Vincent Tuohy
Writer: Karin Connelly
The vaccine uses the body’s own immune system to fight off and kill cancerous tumors. Tuohy, who serves as Shield’s chief science officer, has been working on this theory for the past 11 years.
The next step is to secure FDA approval for human clinical trials, probably within the next two years. Researchers found that a single vaccination could prevent breast tumors from occurring in mice genetically bred to develop breast cancer, while also inhibiting the growth of already existing breast tumors. The research was originally published in Nature Medicine in 2010.
“It works in animals,” says Tuohy. “It’s safe and very effective. We’d like to see women live longer without tumors, not women live longer with tumors.”
Tuohy sees the vaccine as particularly effective in breast cancers that are aggressive and tend to recur. “Triple-negative breast cancer has a higher recurrence rate than other forms of breast cancer and is insensitive to current forms of adjuvant therapy,” he says. “It’s the predominant form of breast cancer that occurs, for example, in women with BRCA1 mutations. “
Tuohy sees potential in eventually immunizing against prostrate and ovarian cancers as well.
Source: Vincent Tuohy
Writer: Karin Connelly
Kelli Hanley Potts has lived in Denver and Albuquerque, where she got involved in the slow food movement, replaced her front lawn with a vegetable garden, and worked for some of those cities' top chefs. When she got the urge to move back home to Cleveland, she knew she wanted to do something food-related.
That's when she stumbled upon a business idea. Despite the rise of the local food movement, most people had no idea how to cook kale, make jam or preserve food. She asked 18 female friends if they knew how to make a pie from scratch, and only two said yes.
Additionally, many people in the local farming movement have trouble explaining and marketing their products to customers, who are largely unfamiliar with them, she explains.
There are no cooking schools in Cleveland that did what she wanted to do -- connect people back to the land and back to their grandmothers' kitchens by teaching them the age-old skills of home economics -- so she decided to create one.
"I didn't want to watch a chef in front of me and drink wine," says Hanley Potts. "I wanted to learn something. I wanted to reconnect people to the lineage of the table, help them build their own table culture."
She recently launched the Agrarian Collective, an earth-to-table lifestyle school. Her mobile cooking school is offering classes this fall that cover topics like roasting your own coffee, fermented and cultured foods, and discovering local apples, among others. She'll be teaching students how to make the perfect pesto at this weekend's Cleveland Flea.
She was aided by a $5,000 low-interest loan from Bad Girl Ventures, which enabled her to purchase supplies and begin reaching out to chefs and farmers as partners.
"This is like home ec, but not quite as official and nerdy," she says. "It's about reconnecting people. All these things we once learned and were taught, they're missing. We're teaching people the 'how' of home."
Source: Kelli Hanley Potts
Writer: Lee Chilcote
That's when she stumbled upon a business idea. Despite the rise of the local food movement, most people had no idea how to cook kale, make jam or preserve food. She asked 18 female friends if they knew how to make a pie from scratch, and only two said yes.
Additionally, many people in the local farming movement have trouble explaining and marketing their products to customers, who are largely unfamiliar with them, she explains.
There are no cooking schools in Cleveland that did what she wanted to do -- connect people back to the land and back to their grandmothers' kitchens by teaching them the age-old skills of home economics -- so she decided to create one.
"I didn't want to watch a chef in front of me and drink wine," says Hanley Potts. "I wanted to learn something. I wanted to reconnect people to the lineage of the table, help them build their own table culture."
She recently launched the Agrarian Collective, an earth-to-table lifestyle school. Her mobile cooking school is offering classes this fall that cover topics like roasting your own coffee, fermented and cultured foods, and discovering local apples, among others. She'll be teaching students how to make the perfect pesto at this weekend's Cleveland Flea.
She was aided by a $5,000 low-interest loan from Bad Girl Ventures, which enabled her to purchase supplies and begin reaching out to chefs and farmers as partners.
"This is like home ec, but not quite as official and nerdy," she says. "It's about reconnecting people. All these things we once learned and were taught, they're missing. We're teaching people the 'how' of home."
Source: Kelli Hanley Potts
Writer: Lee Chilcote
As millenials, empty nesters and other demographic groups flock to downtowns across Ohio, business improvement districts -- or BIDs -- are playing an important role in ensuring that these areas are clean and safe and that residents, office workers and property owners have the amenities they need to thrive.
A business improvement district is a defined area in which property owners pay an additional tax in order to fund projects and services that enhance the area. Downtown Cleveland has a BID, and the organization provides basic "clean and safe" services, organizes events and markets downtown to prospective residents, visitors and businesses.
This week, Downtown Cleveland Alliance, which manages the downtown BID, organized the first all-Ohio BID conference, bringing together BID leaders from across the state to network and learn about issues they share in common.
"It came from the idea that there's not a unifying organization or conference for BIDs," says Anna Beyerle with DCA. "We can learn a lot from other BIDs across Ohio. The idea was to get in the same room and throw out ideas and best practices."
Topics included food truck legislation, downtown transportation, farmers markets, placemaking, and office and retail recruitment strategies.
Participants also enjoyed several tours of downtown Cleveland and the surrounding area and had a chance to learn from Cleveland's redevelopment.
Beyerle says the conference will help BIDs, such as the one in downtown Cleveland, to become more effective. "We're up for renewal in a couple years, and we're looking at how we can improve."
Source: Anna Beyerle
Writer: Lee Chilcote
A business improvement district is a defined area in which property owners pay an additional tax in order to fund projects and services that enhance the area. Downtown Cleveland has a BID, and the organization provides basic "clean and safe" services, organizes events and markets downtown to prospective residents, visitors and businesses.
This week, Downtown Cleveland Alliance, which manages the downtown BID, organized the first all-Ohio BID conference, bringing together BID leaders from across the state to network and learn about issues they share in common.
"It came from the idea that there's not a unifying organization or conference for BIDs," says Anna Beyerle with DCA. "We can learn a lot from other BIDs across Ohio. The idea was to get in the same room and throw out ideas and best practices."
Topics included food truck legislation, downtown transportation, farmers markets, placemaking, and office and retail recruitment strategies.
Participants also enjoyed several tours of downtown Cleveland and the surrounding area and had a chance to learn from Cleveland's redevelopment.
Beyerle says the conference will help BIDs, such as the one in downtown Cleveland, to become more effective. "We're up for renewal in a couple years, and we're looking at how we can improve."
Source: Anna Beyerle
Writer: Lee Chilcote
clinic's cosgrove aims to improve health of residents and city
In a lengthy Forbes feature titled "City Surgeon: Can The Cleveland Clinic Save Its Hometown?" writer Matthew Herper reports on Delos “Toby” Cosgrove's tenure at the Cleveland Clinic and his efforts to leverage healthcare to improve the Clinic's neighborhood and the region's economy.
"The rough old neighborhood is a distant memory, replaced by a gleaming testament to modern medicine stretching out over 46 buildings and covering 167 acres. Protected by a dedicated 141-trooper force of state police, there is a conference center, a fancy hotel and a farmers’ market. Over Cosgrove’s tenure the clinic’s revenues have nearly doubled to $6.2 billion."
But Cosgrove's biggest brainstorm was to build a "giant mall for hospital buyers."
"Think about the things that go into a hospital. Shades, televisions, chairs, tables, wall coverings, all the medical gear, the operating tables, you name it,” Cosgrove is quoted in the piece.
"What is emerging is an Epcot Center for med tech. GE Healthcare, Siemens, Philips Health Care and Cardinal Health are among the 22 confirmed tenants in the soon-to-be-completed center. Next door, Bennett has already booked conventions that will bring 89,395 attendees this year and 100,400 next. By the end of 2016, he says, bookings should be enough to pay back the $465 million it took to construct both buildings."
“It will begin to influence the city as it comes back and make it a destination medical city,” Cosgrove predicts.
Read the rest of the article here.
"The rough old neighborhood is a distant memory, replaced by a gleaming testament to modern medicine stretching out over 46 buildings and covering 167 acres. Protected by a dedicated 141-trooper force of state police, there is a conference center, a fancy hotel and a farmers’ market. Over Cosgrove’s tenure the clinic’s revenues have nearly doubled to $6.2 billion."
But Cosgrove's biggest brainstorm was to build a "giant mall for hospital buyers."
"Think about the things that go into a hospital. Shades, televisions, chairs, tables, wall coverings, all the medical gear, the operating tables, you name it,” Cosgrove is quoted in the piece.
"What is emerging is an Epcot Center for med tech. GE Healthcare, Siemens, Philips Health Care and Cardinal Health are among the 22 confirmed tenants in the soon-to-be-completed center. Next door, Bennett has already booked conventions that will bring 89,395 attendees this year and 100,400 next. By the end of 2016, he says, bookings should be enough to pay back the $465 million it took to construct both buildings."
“It will begin to influence the city as it comes back and make it a destination medical city,” Cosgrove predicts.
Read the rest of the article here.