NovelMed Therapeutics, a biotech company founded in 2003 that develops treatments for macular degeneration, announced that it has developed an antibody compound that is effective in treating wet age-related macular degeneration (AMD) and possibly the dry form of the disease as well. AMD affects more than two million people in the United States and is a leading cause of blindness among adults.

Two independent pre-clinical investigations showed that NovelMed's lead comp... Read more >

Modern medicine is constantly innovating ways to improve the length and quality of human life. Cleveland researchers are leading the way with cutting-edge treatments and technologies that can blast a brain tumor with a laser, detect a concussion using an iPad, and test for prostate cancer by way of genetics.

Speaking last week at the annual meeting of the Northeast Ohio Areawide Coordinating Agency (NOACA), the regional transportation planning agency for Northeast Ohio, Executive Director Grace Gallucci promised a more strategic distribution of money for projects and greater emphasis on multi-modal transportation options.

"We want more choices; that's what freedom -- being an American -- is about," she said. "NOACA is not trying to vilify the automobile; we... Read more >

"Failure" is a tough word, particularly for entrepreneurial types throwing so much of their lives into a venture that might go belly up within a few months. However, Paul McAvinchey, creator of TechPint, believes valuable lessons can be learned from disappointment.

Such is the theme of this fall's TechPint conference, a casual gathering for entrepreneurs and investors in Internet technology. Coordinator McAvinchey expects more than 250 of the region's mo... Read more >

The large number of open jobs in the startup community indicates these companies are doing well and growing. But working for a young startup has unique challenges. Recruiters and employers discuss some of the critical qualities required for those looking for a good fit with a startup.

Cleveland Clinic Innovations has launched a spinoff company, Shield Biotech, out of the Lerner Research Institute. Led by Vincent Tuohy, the company is developing a vaccine for breast cancer.

The vaccine uses the body’s own immune system to fight off and kill cancerous tumors. Tuohy, who serves as Shield’s chief science officer, has been working on this theory for the past 11 years. 
 
The next step is to secure FDA approval for human cl... Read more >

Cleveland, like most American cities, has had its challenges regarding segregation. But emerging patterns of desegregation can significantly advance our city's position as a center of innovation. This represents a key opportunity to reconstitute a new American neighborhood model by harnessing the potential of diversification.

Kelli Hanley Potts has lived in Denver and Albuquerque, where she got involved in the slow food movement, replaced her front lawn with a vegetable garden, and worked for some of those cities' top chefs. When she got the urge to move back home to Cleveland, she knew she wanted to do something food-related.

That's when she stumbled upon a business idea. Despite the rise of the local food movement, most people had no idea how to cook kale, make jam or preserve food. ... Read more >

Are you sustainable, Cleveland? That's the question environmentally conscious city officials are asking heading into the fifth annual Sustainable Cleveland 2019 Summit. The initiative to build "a green city on a blue lake" is at the halfway mark, and Cleveland's new chief of sustainability believes Northeast Ohio is meeting the metrics set out a half decade ago.

As summer transitions into fall, we wanted to take a moment to look back on a season filled with family, friends and festive neighborhood gatherings. Throughout it all, Fresh Water photographer Bob Perkoski has been attending and shooting the best summer festivals. This slideshow features captured images from a dozen events.

Nine local biomedical companies were named to this year’s Inc. 5000 list, a tally of the fastest growing companies in the country in terms of jobs and revenue. Inc. measured revenue growth from 2009 to 2012.
 
The list represents companies across every industry, but the number of area biomed companies named to the list is encouraging to the growing biomed industry in Cleveland.
 
“It’s a very exciting time right now in Northeast Ohio for... Read more >

Jason Tilk, a Cleveland Institute of Art graduate, designs award-winning medical innovations for Nottingham Spirk, the Cleveland-based business innovation firm. By night, the wildly creative trailblazer performs Vaudeville-style shows with his wife that incorporate songs, jokes and "bad magic."